Sensors in hot runner systems that can withstand gamma-ray sterilization require radiation-resistant materials to ensure measurement stability under high-energy radiation. These sensors are typically used in pharmaceuticals, biopharmaceuticals, and other applications with extremely high sterility requirements. Their key strength lies in the radiation resistance of the materials and electronic components.
1. Key Characteristics of Gamma-Resistant Sensors
|
Characteristics |
Description |
|
Radiation-Resistant Encapsulation |
Utilizes 30% glass fiber reinforced materials such as LCP (Liquid Crystal Polymer) G-330 HH BK, capable of withstanding gamma irradiation up to 45–75 kGy without embrittlement or performance degradation. |
|
Sensor Type |
Mostly disposable pH, conductivity, or temperature sensors, gamma-sterilized before leaving the factory to avoid secondary contamination. |
|
Electronic Component Protection |
Employs gamma-resistant non-volatile memory (such as DS28E80), capable of withstanding 75 kGy irradiation and preventing data loss. |
|
Measurement Stability |
Even after gamma irradiation, drift remains at extremely low levels (e.g., <0.1 pH per week). |
Typical Applications: Hamilton OneFerm series pH sensors and Mettler Toledo InSUS 310i sensors both support gamma sterilization and are used in disposable bioreactors.
2. Applicable Scenarios and Sterilization Parameters
Sterilization Dosage: Typically 25–50 kGy, up to 75 kGy in some high-requirement scenarios.
Applicable Processes: Single-use biopharmaceutical processes, aseptic filling, cell culture bags, etc.
Compatibility Requirements: The sensor must be validated according to ISO 11137 standards to ensure normal function after irradiation.
3. Recommended Brands and Models
Hamilton OneFerm pH Sensor: Designed for single use, gamma irradiation resistant, suitable for bioreactors.
Mettler Toledo InSUS 310i: Gamma and X-ray resistant, integrated into single-use process bags.
Broadley-James SG310: Gamma irradiation sterilized single-use pH sensor with Kleenpak® connector.
